Disabling USB ports on a computer by the administrator is easy and well documented on Microsoft’s support site. But protecting USB ports with a password so that only authorized users can access it, is a feature not to be found on Windows. To do this we have to use a software called PenyuUSB.
PenyuUSB is a software that enables the administrator to quickly enable or disable USB ports on a computer without going through the hassles of editing the Registry or the Group Policy. With a simple click of a button, USB ports can be toggled on and off.
But that’s not all. PenyuUSB has the ability to protect the toggle access to the USB ports with a password. The administrator sets a password which prevents other users from re-enabling access to the USB ports.
PenyuUSB is free but registration is required.
Update: PenyuUSB works with Windows XP (.Net 3.5 Framework required), Windows Vista and 7.